Patents and Inventions

Patents - Issued

• Xiaohua Huang, “Methods and systems for direct real-time sequencing of single DNA molecules”, United States Patent No. US 9,382,584 B2 (PDF) (Issued July 5, 2016).
• Xiaohua Huang and Kristopher D Barbee, “Methods and devices for biomolecular arrays”, United States Patent No. US 9063133B2 (PDF) (Issued June 23, 2015).
• Xiaohua Huang and Eric E Roller, “Mostly natural DNA sequencing by synthesis”, United States Patent No. US 8772473 B2 (PDF) (Issued July 8, 2014).
• Xiaohua Huang and Paul M. Lizardi, “Single molecule analysis and target-mediated ligation of bipartite primers”, United States Patent No. US 6316229 B1 (PFD) (Issued November 13, 2001).

Patents - Pending

• Xiaohua Huang, “Duplicating DNA with contiguity barcodes for genome and epigenome sequencing”, US application No. US20160265039A1, WIPO International Publication No. WO 2015/073693 A1 (May, 2015)
• Kun Zhang and Xiaohua Huang, “Accurate genome sequencing of single cells by single-stranded amplification and sequencing”, Patent Application. No. PCT/US2013/059086. WIPO International Publication No. WO 2014043140 A1 (2014).
• Xiaohua Huang, “Hybrid nanopore devices and methods for single-molecule protein sequencing”, Patent Application (2019).

Invention disclosures

• Xiaohua Huang, “Methods of DNA multiplexed Encoding”, UCSD invention disclosure (2013).