Kwang-Seuk Ko


Post-Doctoral Researcher

University of California, San Diego
Department of Bioengineering
471 Powell-Focht Bioengineering Hall
9500 Gilman Drive
La Jolla, CA 92093-0412



Kwang-Seuk obtained his B.S degree in biochemistry and Ph.D. in chemistry from Iowa State University. As his Ph.D. program, he successfully accomplished many projects which include multiple chemical syntheses and then tested these molecules for bioactivity with bacterial and eukaryotic enzymes. He was awarded the Esther C. and George E. Daniel Fellowship for excellence in research as well as the Mary K. and Velmer A. Fassel Award.

He is currently a post-doctoral scholar at the University of California-San Diego. As his first postdoctoral researcher he had been assigned two challenging projects. His first priority project was a high-throughput method for the fabrication of polycarbonate based bioactive platforms. He also finished a second research project studying the compound responsible for a severe human skin disease known as Buruli’s ulcer.

Currently, his research area involves include: 1) developing a novel solid-phase methods for the synthesis of fluorescence-labeled nucleotides with cleavable linkers for sequencing applications, 2) developing chemistry for charging tRNA molecules with fluorescence-labeled amino acids for engineering DNA/RNA polymerases with FRET sensors to study the dynamics of chemo-mechanical process of enzymatic catalysis by the polymerases, 3) participating in the development of new READS genome sequencing technology.